Actually, the use of the eggs is not limited to the one-at-a-time application.  If you are in search of dolls mainly, you may put an upper fragment + a lower fragment + a full egg to yield 2 dolls, guaranteed.  Otherwise, the egg has its normal various potentials.  But otherwise, one at a time is the way to go.  There is a set of html files under the support folder in your D2 directory that I think you'll find quite helpful and informative.  They include runewords, cube recipes, unique and set item lists, just to name a few.  Check it out when you have a few moments.  Beats having to chase down all that information on your own.